I don't think Jesus is returning to the Earth soon to judge us all, however no man knows the date at which He will return so no point in discussing this. Nevertheless, human society has suffered this type of cultural issue before. Before Rome collapsed and became small isolated feudal communities, it was in the peak of a degenerate gender obsession that had gripped most of its citizens, along with a lot of emperors. (See the story of Emperor Elagabalus. His personal life insights you on the problems Rome had at the time concerning gender). After this feud, Rome stopped existing and Europe regressed a few decades in technology, but no long-term harm was observed. What's stopping this situation from being the exact same? If the US collapses due to this division, it's going to be chaotic but it WILL not be the end for us all.